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buprenorphine transdermal and diazepam equally increase sedation. Steer clear of or Use Alternate Drug. Limit use to individuals for whom choice treatment solutions are inadequateenasidenib will enhance the amount or effect of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Enasidenib (a weak CYP2C19 inhibitor) may pos